Sunday, August 30, 2009

Reduced Diversity of Faecal Microbiota in Crohn's Disease

Another research study (related to previous posts) found that:
... a reduced complexity of the bacterial phylum Firmicutes as a signature of the faecal microbiota in patients with CD. It also indicated the presence of new bacterial species.
The question is why is there less of that bacteria? Overgrowth from other bacteria? Lack of exposure to that bacteria? Hyper-immune response to that bacteria that result in immune imbalances due to the reduction in modulating or regulating effects of the bacteria?

Another interesting thing to follow-up on: small bowel bacterial overgrowth syndrome. Could there be a relationship with Crohns?

1 comment:

  1. Diminished decent variety of fecal microbiota in Crohn's illness uncovered by a metagenomic approach. Foundation AND AIM: A job for the intestinal microbial network (microbiota) in the beginning and chronicity of Crohn's infection is unequivocally suspected.

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